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While Western clinical trial data on the specific combination is limited, the individual evidence bases for each peptide are substantial, and their mechanisms are complementary rather than redundant

510 Only a small percentage (8%) of older adults with dementia do not receive help from family members or other informal care providers

Additionally, intra-portal insulin regulates hepatic secretion of IGFBP-1, an inhibitor of IGF-I action

Healthcare professionals should approach disclosures of combined peptide use with a non-judgemental but clinically thorough assessment, and provide harm-minimisation advice where appropriate

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